{"title":"Vitamin B12 \u0026 B Vitamins","description":"\u003cp\u003eWe stock the active forms of the B vitamins that many standard products leave out. Our vitamin B12 range covers methylcobalamin, adenosylcobalamin and hydroxocobalamin, in liquid drops and capsules. Vitamin B6 is available as P5P, the coenzyme form the body uses directly, and vitamin B2 as R5P. These forms suit people who prefer their vitamins pre-converted and ready to work.\u003c\/p\u003e\u003cp\u003eTo compare forms, read the B vitamin entries in the \u003ca href=\"\/apps\/learn\"\u003eHealth Reference Library\u003c\/a\u003e or ask \u003ca href=\"\/pages\/nutri365\"\u003e\u003cstrong\u003eNutri365\u003c\/strong\u003e\u003c\/a\u003e, our AI health expert.\u003c\/p\u003e","products":[{"product_id":"vitamin-b12-methylcobalamin-capsules","title":"Vitamin B12 Methylcobalamin Capsules","description":"\u003cp\u003e\u003cstrong\u003eSupport nerve function and methylation with the most active form of B12\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethylcobalamin only, no other B12 forms.\u003c\/strong\u003e These capsules contain methylcobalamin as the sole form of vitamin B12, with no adenosylcobalamin, cyanocobalamin or hydroxocobalamin. For the mitochondrial form see \u003ca href=\"\/products\/vitamin-b12-adenosylcobalamin-capsules\"\u003eVitamin B12 Adenosylcobalamin Capsules\u003c\/a\u003e, or \u003ca href=\"\/products\/tri-b12-vitamin-liquid\"\u003eTRI-B12 Liquid\u003c\/a\u003e for all three forms in one bottle. For a gentler starting dose see \u003ca href=\"\/products\/vitamin-b12-methylcobalamin-liquid\"\u003eVitamin B12 Methylcobalamin Liquid\u003c\/a\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e1000 mcg methylcobalamin per capsule\u003c\/strong\u003e (40000% NRV)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eVegetarian capsule shell\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in the UK\u003c\/strong\u003e by Metabolics\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEach capsule provides 1000mcg of vitamin B12 as methylcobalamin, the cytoplasmic active form of B12 that serves as a cofactor for the enzyme methionine synthase. This enzyme converts homocysteine to methionine, a reaction that is central to the methylation cycle. Methylation is one of the body's most important biochemical processes, governing gene expression, neurotransmitter production (serotonin, dopamine, noradrenaline), detoxification, myelin sheath maintenance and histamine clearance.\u003c\/p\u003e\u003cp\u003eMethylcobalamin is the most commonly recommended active B12 form because methylation dysfunction is widespread (driven by MTHFR gene variants, nutritional deficiencies and high toxic burden). At 1000mcg per capsule, this provides a beneficial dose appropriate for addressing B12 deficiency, supporting methylation, managing elevated homocysteine and neurological support. The capsule format provides a higher dose than the liquid versions, making it the preferred choice when a substantial daily B12 dose is required. The vegetarian capsule shell makes this suitable for most dietary requirements.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNerve repair\u003c\/strong\u003e and brain function\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDirect methylation\u003c\/strong\u003e no conversion\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMost active\u003c\/strong\u003e form of B12\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eEach capsule contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e1000 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e40000%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003eCellulose, Hydroxypropyl Methylcellulose (capsule), Methylcobalamin.\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 capsule per day with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eTaking with a meal supports absorption. For those new to methylcobalamin who have known methylation sensitivities (COMT variants, histamine intolerance), start with the liquid form (86.5mcg per drop) as the lower dose allows gentler introduction. Some individuals experience overstimulation, anxiety or insomnia when starting methylcobalamin at high doses, which typically resolves by starting low and increasing gradually.\u003c\/p\u003e\u003cp\u003eFor comprehensive B12 coverage, pair with \u003ca href=\"\/products\/vitamin-b12-adenosylcobalamin-capsules\"\u003eVitamin B12 Adenosylcobalamin Capsules\u003c\/a\u003e to support both cytoplasmic methylation and mitochondrial energy production simultaneously.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"Default Title","offer_id":47594908549394,"sku":"METHY90C","price":20.52,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB12Methylcobalamin_3ea6ce34-f22e-4f7e-808d-7fd9b1aa5c84.jpg?v=1740699573"},{"product_id":"vitamin-b2-r5p-liquid","title":"Vitamin B2 R5P Liquid","description":"\u003cp\u003e\u003cstrong\u003eSupport energy with rapid absorption liquid riboflavin, studied in the context of migraine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eR5P only, the active form of B2.\u003c\/strong\u003e This liquid contains riboflavin 5 phosphate (R5P) as its sole form of vitamin B2, not plain riboflavin. The only other ingredient is citric acid, which stabilises the R5P in solution. For higher B2 doses, see \u003ca href=\"\/products\/vitamin-b2-r5p-capsules\"\u003eVitamin B2 R5P Capsules\u003c\/a\u003e at 47.5mg per capsule.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e1.6 mg R5P per 10-drop serving\u003c\/strong\u003e (114% NRV)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e138 servings per 100ml bottle\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eBottle sizes: 100ml, 250ml and 500ml\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan\u003c\/strong\u003e, gluten free, dairy free, nut free\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in the UK\u003c\/strong\u003e by Metabolics\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrop-based dosing\u003c\/strong\u003e for a gentle maintenance level\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eA liquid vitamin B2 providing 1.6mg of riboflavin as riboflavin 5 phosphate (R5P) per 10 drop serving in a purified water base with citric acid. R5P is the active coenzyme form of vitamin B2 that participates directly in flavocoenzyme reactions without requiring conversion. The liquid format provides a lower dose per serving than the capsules (1.6mg vs 47.5mg), making it suitable for those who need gentle B2 supplementation, children, or those who have difficulty swallowing capsules.\u003c\/p\u003e\u003cp\u003eRiboflavin 5 phosphate supports the MTHFR enzyme (methylation), glutathione reductase (antioxidant recycling), the electron transport chain (energy production) and the metabolism of vitamins B6 and folate to their active forms. The citric acid in the formulation stabilises the R5P in solution. The bottle provides 138 servings per 100ml.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid absorption\u003c\/strong\u003e for energy support\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStudied for migraine\u003c\/strong\u003e with regular use\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquid form\u003c\/strong\u003e for fast uptake\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e10 drops contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRiboflavin (Vitamin B2)\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e1.6 mg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e114%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003ePurified Water, Riboflavin 5 Phosphate, Citric acid.\u003c\/p\u003e\n\u003cp\u003e1 serving = 10 drops | 138 servings per 100ml\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 10 drops per day in water with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe drops can be added to a glass of water, juice or taken directly. This liquid format provides a maintenance level dose of active B2. For those requiring beneficial B2 doses (such as for migraine prevention or intensive methylation support), the capsule form at 47.5mg per capsule is more practical. The liquid is best suited for daily maintenance, sensitive individuals or as part of a broader liquid supplement routine.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"100ml","offer_id":50182941212946,"sku":"RIBO0100T","price":25.44,"currency_code":"GBP","in_stock":false},{"title":"250ml","offer_id":50182941245714,"sku":"RIBO0250T","price":39.6,"currency_code":"GBP","in_stock":false},{"title":"500ml","offer_id":50182941278482,"sku":"RIBO0500T","price":66.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB2R5PLiquid_5e5c73ae-8a89-433a-90a9-5a4e5456b727.jpg?v=1740699394"},{"product_id":"b12-and-folate","title":"B12 and Folate","description":"\u003cp\u003e\u003cstrong\u003eSupport energy, mood and red blood cell production with active B12 and folate\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eB12 and Folate provides high dose methylated forms of two of the most commonly deficient B vitamins in a single capsule. Each capsule delivers 1000mcg of folate as calcium L-methylfolate and 1000mcg of vitamin B12 as methylcobalamin.\u003c\/p\u003e\u003cp\u003eThese two nutrients work closely together in the methylation cycle, which governs DNA synthesis, red blood cell production, nerve function and homocysteine metabolism. Deficiency in either can cause fatigue, brain fog, low mood, nerve symptoms and anaemia.\u003c\/p\u003e\u003cp\u003eBoth are provided in their active methylated forms, which is particularly important for the estimated 30 to 40% of people who carry MTHFR gene variants that impair the conversion of folic acid and cyanocobalamin into their usable forms. Methylfolate and methylcobalamin bypass this conversion entirely.\u003c\/p\u003e\u003cp\u003eB12 deficiency is common in vegetarians, vegans, older adults and anyone taking metformin or proton pump inhibitors. Folate requirements increase during pregnancy, preconception and in anyone with elevated homocysteine levels.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMore energy\u003c\/strong\u003e and less tiredness\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHealthy blood cells\u003c\/strong\u003e and oxygen delivery\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive forms\u003c\/strong\u003e for direct cellular use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eEach capsule contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFolate\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e1000 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e500%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e1000 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e40000%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003eCellulose, Hydroxypropyl Methylcellulose (capsule), Calcium L Methyl Folate, Methylcobalamin.\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 capsule per day with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOne capsule provides the full beneficial dose. Taking with any meal improves tolerability.\u003c\/p\u003e\u003cp\u003eIf you are taking this to correct a known deficiency, your practitioner may recommend a higher dose for the initial loading period. Retest B12 and folate levels after 8 to 12 weeks to confirm the response.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"Default Title","offer_id":47594917855506,"sku":"B12FOL90C","price":27.6,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/B12andFolate_e593f980-baa6-49af-a8e6-23df97f9913a.jpg?v=1740699368"},{"product_id":"vitamin-b2-r5p-capsules","title":"Vitamin B2 R5P Capsules","description":"\u003cp\u003e\u003cstrong\u003eSupport energy metabolism with active riboflavin (R5P), studied in the context of migraine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEach capsule provides 47.5mg of vitamin B2 as riboflavin 5 phosphate (R5P), the active coenzyme form that the body uses directly without requiring hepatic conversion. Standard riboflavin must be phosphorylated in the liver to become R5P before it can function as a cofactor for flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), the two flavocoenzymes involved in energy production, antioxidant defence and the metabolism of other B vitamins.\u003c\/p\u003e\u003cp\u003eR5P is a cofactor for the MTHFR enzyme (connecting riboflavin directly to methylation capacity), glutathione reductase (recycling oxidised glutathione back to its active reduced form) and the electron transport chain (mitochondrial energy production). Riboflavin at doses of 200 to 400mg daily has specific evidence for migraine prevention. At 47.5mg per capsule, the dose can be scaled from maintenance to beneficial levels. The vegetarian capsule shell makes this suitable for most dietary requirements. Note: vitamin B2 turns urine bright yellow, which is harmless and indicates absorption.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy metabolism\u003c\/strong\u003e and less fatigue\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFewer migraines\u003c\/strong\u003e clinically shown\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive form\u003c\/strong\u003e ready for use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eEach capsule contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e\n\u003cp\u003e%NRV*\u003c\/p\u003e\n\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eRiboflavin (Vitamin B2)\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e47.5 mg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e3393%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003eCellulose, Riboflavin 5 Phosphate, Hydroxypropyl Methylcellulose (capsule).\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 capsule per day with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eFor general maintenance and methylation support, 1 capsule daily is appropriate. For migraine prevention, higher doses (up to 400mg daily, approximately 8 capsules) are used in clinical research, though this should be guided by a healthcare professional. The R5P form is particularly important for those with liver dysfunction or MTHFR variants, as both conditions can impair the conversion of standard riboflavin to its active form.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"Default Title","offer_id":47594919952658,"sku":"BCOM260C","price":20.93,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB2R5P_a7dfe518-3231-4147-9857-2d0c269de6ff.jpg?v=1740699310"},{"product_id":"vitamin-b6-p5p-liquid","title":"Vitamin B6 P5P Liquid","description":"\u003cp\u003e\u003cstrong\u003eBalance hormones and support brain chemistry with rapid absorption active B6\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eP5P only, the active form of B6.\u003c\/strong\u003e This liquid contains pyridoxal 5 phosphate (P5P) as its sole form of vitamin B6, not pyridoxine hydrochloride. The only other ingredients are purified water and potassium carbonate, which stabilises the P5P in solution. For higher B6 doses, see \u003ca href=\"\/products\/vitamin-b6-p5p-capsules\"\u003eVitamin B6 P5P Capsules\u003c\/a\u003e at 34mg per capsule.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e848 mcg P5P per drop\u003c\/strong\u003e (61% NRV), 1 drop = 1 serving\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e1333 servings per 100ml bottle\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eBottle sizes: 100ml and 250ml\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan\u003c\/strong\u003e, gluten free, dairy free, nut free\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in the UK\u003c\/strong\u003e by Metabolics\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrop-by-drop dose control\u003c\/strong\u003e for precise titration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eA liquid vitamin B6 providing 848mcg (0.85mg) of pyridoxal 5 phosphate (P5P) per single drop in a purified water base with potassium carbonate. P5P is the active coenzyme form of vitamin B6 that participates directly in over 150 enzymatic reactions without requiring liver conversion. The liquid format provides precise dose control and is ideal for those who need lower B6 doses, children, or those who prefer liquid supplements.\u003c\/p\u003e\u003cp\u003eAt 848mcg per drop, this provides 61% of the NRV in a single drop, with the flexibility to increase by adding additional drops. The potassium carbonate in the formulation helps maintain the alkaline pH at which P5P is most stable in solution. The bottle provides 1333 servings per 100ml.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHormone balance\u003c\/strong\u003e and brain chemistry\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid absorption\u003c\/strong\u003e for faster effect\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive P5P\u003c\/strong\u003e for direct use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e1 drop contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e848 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e61%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003ePurified Water, Pyridoxal 5 Phosphate, Potassium Carbonate.\u003c\/p\u003e\n\u003cp\u003e1 serving = 1 drop | 1333 servings per 100ml\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 drop per day in water with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe drop can be added to water or taken directly. For those requiring higher B6 doses, multiple drops can be used (for example, 2 drops provides 1.7mg). For beneficial B6 dosing (PMS, mood support, methylation), the capsule form at 34mg is more practical. The liquid is best suited for maintenance supplementation, dose titration or inclusion in a liquid supplement routine alongside other liquid vitamins.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"100ml","offer_id":50182951928082,"sku":"PYRI0100T","price":22.08,"currency_code":"GBP","in_stock":true},{"title":"250ml","offer_id":50182951960850,"sku":"PYRI0250T","price":31.1,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB6P5PLiquid_8cc0fa16-48be-4dc9-841d-6d48a3fafcf9.jpg?v=1740699227"},{"product_id":"methyltetrahydrofolate","title":"Methyltetrahydrofolate","description":"\u003cp\u003e\u003cstrong\u003eSupport methylation and cellular function with active folate for MTHFR gene variations\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis is folate in its most bioactive form: 5 methyltetrahydrofolate (5 MTHF), provided as calcium L methylfolate at 1000mcg (500% NRV) per capsule. Unlike standard folic acid (the synthetic form found in most supplements and fortified foods), methylfolate does not require conversion by the enzyme MTHFR before the body can use it. This is significant because an estimated 30 to 40% of the population carry genetic variants of the MTHFR gene that reduce their ability to convert folic acid into its active form.\u003c\/p\u003e\u003cp\u003eFor these individuals, taking standard folic acid may result in unmetabolised folic acid circulating in the blood without providing the folate dependent functions the body needs: DNA synthesis and repair, methylation (critical for gene expression, detoxification and neurotransmitter production), red blood cell formation and homocysteine clearance. At 1000mcg, this provides a beneficial dose appropriate for preconception, pregnancy, MTHFR support, mood support and homocysteine management. The capsule contains cellulose filler and a vegetarian capsule shell.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive folate\u003c\/strong\u003e for MTHFR variations\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBetter methylation\u003c\/strong\u003e and cell repair\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMood support\u003c\/strong\u003e via neurotransmitters\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eEach capsule contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFolate\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e1000 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e500%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003eCellulose, Hydroxypropyl Methylcellulose (capsule), Calcium L-Methyl Folate.\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 capsule per day with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThis product is suitable for anyone who needs folate supplementation but wants to bypass the conversion step required by folic acid. It is particularly relevant for those who know they carry MTHFR variants (C677T or A1298C), those with elevated homocysteine, women planning pregnancy, and those using folate for mood or methylation support.\u003c\/p\u003e\u003cp\u003eIf taking alongside vitamin B12, ensure the B12 is also in its active form (methylcobalamin or adenosylcobalamin) for consistent methylation support. Folate and B12 work together in the methylation cycle and should ideally be supplemented as a pair when either is taken at beneficial doses.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"Default Title","offer_id":47594929914130,"sku":"METHYLTHF60C","price":23.52,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/Methyltetrahydrofolate_39b4f841-4654-4255-a80b-7a02904cfdfa.jpg?v=1740699137"},{"product_id":"vitamin-b6-p5p-capsules","title":"Vitamin B6 P5P Capsules","description":"\u003cp\u003e\u003cstrong\u003eSupport neurotransmitter production and hormone balance with active B6 (P5P)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEach capsule provides 34mg of vitamin B6 as pyridoxal 5 phosphate (P5P), the active coenzyme form used directly by the body in over 150 enzymatic reactions. P5P is a cofactor for amino acid metabolism, neurotransmitter synthesis (serotonin, dopamine, GABA, noradrenaline), haemoglobin production, homocysteine clearance (as part of the transsulfuration pathway) and glycogen phosphorylase (releasing stored energy from muscles and liver).\u003c\/p\u003e\u003cp\u003eStandard pyridoxine (the form in most B6 supplements) requires conversion by the liver enzyme pyridoxal kinase to become P5P. Individuals with liver dysfunction, genetic variations or high toxic burden may have impaired conversion. P5P bypasses this step entirely. Vitamin B6 is particularly relevant for premenstrual symptoms (PMS), mood disorders, nausea during pregnancy (at lower doses), carpal tunnel syndrome and as part of methylation protocols. At 34mg per capsule, this is a beneficial dose. The vegetarian capsule shell makes this suitable for most dietary requirements.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMood balance\u003c\/strong\u003e via serotonin and dopamine\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHormone regulation\u003c\/strong\u003e and PMS relief\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive P5P\u003c\/strong\u003e no liver conversion\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eEach capsule contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B6\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e34 mg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e2429%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003eCellulose, Pyridoxal 5 Phopshate Hydroxypropyl Methylcellulose (capsule).\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 capsule per day with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eFor most applications, 1 capsule daily is sufficient. B6 is water soluble and excess is excreted, but prolonged use of very high doses (above 100mg daily) has been associated with peripheral neuropathy in some individuals. At 34mg, this product is well within safe long term use levels.\u003c\/p\u003e\u003cp\u003eFor PMS support, P5P is often combined with magnesium (particularly magnesium bisglycinate). For methylation protocols, it pairs with methylfolate and methylcobalamin as the three key methylation cofactors.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"60 caps","offer_id":50182948454674,"sku":"B6P5P60C","price":21.84,"currency_code":"GBP","in_stock":true},{"title":"120 caps","offer_id":50182948487442,"sku":"B6P5P120C","price":28.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB6P5P.jpg?v=1740699107"},{"product_id":"biotin","title":"Biotin","description":"\u003cp\u003e\u003cstrong\u003eSupport healthy hair growth, strong nails and vibrant skin with high strength biotin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBiotin (vitamin B7) is a water soluble B vitamin that supports the health of hair, skin and nails. It also plays an essential role in energy metabolism, helping the body convert fats, carbohydrates and proteins into usable energy.\u003c\/p\u003e\u003cp\u003eEach capsule provides 8000mcg (8mg) of biotin, which is a high beneficial dose designed for targeted support of hair, skin and nail health. The adequate intake for biotin is only 50mcg, but higher doses are widely used in clinical practice for hair thinning, brittle nails and skin conditions, with research supporting doses of 2500 to 10000mcg for these purposes.\u003c\/p\u003e\u003cp\u003eBiotin deficiency, while relatively uncommon, can cause hair thinning, skin rashes and brittle nails. Certain populations are more prone to low levels, including pregnant women, people on long term antibiotics, and those with digestive conditions that impair nutrient absorption.\u003c\/p\u003e\u003cp\u003eNote: high dose biotin can interfere with certain blood tests, including thyroid function tests and troponin (heart attack marker). If you are having blood tests, inform your healthcare provider that you are taking biotin and consider stopping it 48 to 72 hours before testing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eThicker hair\u003c\/strong\u003e and healthier growth\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStronger nails\u003c\/strong\u003e that resist breaking\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVibrant skin\u003c\/strong\u003e and cell renewal\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eEach capsule contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBiotin\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e8000 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e16,000%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e(Vitamin B7)\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003eCellulose, Hydroxypropyl Methylcellulose (capsule), Biotin.\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 capsule per day with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOne capsule provides the full beneficial dose. Biotin is water soluble, so any excess is excreted rather than stored. Taking with food improves absorption.\u003c\/p\u003e\u003cp\u003eAllow 3 to 6 months of consistent use to see meaningful changes in hair and nail quality, as these tissues grow slowly.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"Default Title","offer_id":47594936041746,"sku":"BIOTI60C","price":28.56,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/Biotin_f5f43548-407e-410e-adb3-7833a847f315.jpg?v=1740698973"},{"product_id":"vitamin-b12-adenosylcobalamin-liquid","title":"Vitamin B12 Adenosylcobalamin Liquid","description":"\u003cp\u003e\u003cstrong\u003eBoost cellular energy quickly with sublingual adenosylcobalamin B12\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdenosylcobalamin only, no other B12 forms.\u003c\/strong\u003e This liquid contains adenosylcobalamin as its sole form of vitamin B12, with no methylcobalamin, cyanocobalamin or hydroxocobalamin, and no other ingredients beyond purified water. If you want methylcobalamin alongside it, see \u003ca href=\"\/products\/vitamin-b12-methylcobalamin-liquid\"\u003eVitamin B12 Methylcobalamin Liquid\u003c\/a\u003e, or \u003ca href=\"\/products\/tri-b12-vitamin-liquid\"\u003eTRI-B12 Liquid\u003c\/a\u003e for all three forms in one bottle.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e76 mcg adenosylcobalamin per drop\u003c\/strong\u003e (3040% NRV), 1 drop = 1 serving\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e1754 servings per 100ml bottle\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eAvailable in 100ml, 250ml and 500ml bottles\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan\u003c\/strong\u003e, gluten free, dairy free, nut free\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in the UK\u003c\/strong\u003e by Metabolics\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSublingual option\u003c\/strong\u003e: hold under the tongue for 30 seconds\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eA liquid vitamin B12 providing 76mcg of adenosylcobalamin per single drop in a purified water base. Adenosylcobalamin is the mitochondrial form of B12, serving as a cofactor for the enzyme methylmalonyl CoA mutase within the mitochondria. This enzyme is essential for energy production from odd chain fatty acids and branched chain amino acids. When adenosylcobalamin is insufficient, methylmalonic acid accumulates, which can be measured in blood or urine as a specific marker of functional B12 deficiency.\u003c\/p\u003e\u003cp\u003eThe liquid format offers two advantages over capsules: flexible dosing (the dose can be adjusted drop by drop) and the option for sublingual absorption (drops placed under the tongue are absorbed directly into the bloodstream, bypassing the digestive system). This is particularly valuable for those with B12 absorption issues due to low stomach acid, intrinsic factor deficiency, pernicious anaemia or digestive conditions. The bottle provides 1754 servings per 100ml, making it exceptionally economical for long term use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuick energy\u003c\/strong\u003e via sublingual absorption\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular fuel\u003c\/strong\u003e for mitochondria\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive B12\u003c\/strong\u003e no conversion needed\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e1 drop contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e76 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e3040%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003ePurified Water, Adenosylcobalamin.\u003c\/p\u003e\n\u003cp\u003e1 serving = 1 drop | 1754 servings per 100ml\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 drop per day in water with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe drop can be added to a small glass of water, taken directly on the tongue or held under the tongue for 30 seconds for sublingual absorption. For those specifically targeting mitochondrial energy, 2 to 3 drops daily may be used.\u003c\/p\u003e\u003cp\u003eFor comprehensive B12 support covering both mitochondrial and methylation functions, pair with Vitamin B12 Methylcobalamin Liquid, or use TRI B12 Liquid which provides all three forms in a single product.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"100ml","offer_id":50182858047762,"sku":"ADE0100T","price":25.06,"currency_code":"GBP","in_stock":true},{"title":"250ml","offer_id":50182858080530,"sku":"ADE0250T","price":34.56,"currency_code":"GBP","in_stock":false},{"title":"500ml","offer_id":50182858113298,"sku":"ADE0500T","price":53.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB12AdenosylcobalaminLiquid_c383fb71-1722-4b76-86ca-3045c98b6ba1.jpg?v=1740698945"},{"product_id":"vitamin-b12-adenosylcobalamin-capsules","title":"Vitamin B12 Adenosylcobalamin Capsules","description":"\u003cp\u003e\u003cstrong\u003eBoost mitochondrial energy production with active adenosylcobalamin B12\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdenosylcobalamin only, no other B12 forms.\u003c\/strong\u003e These capsules contain adenosylcobalamin as the sole form of vitamin B12, with no methylcobalamin, cyanocobalamin or hydroxocobalamin. For the methylation form see \u003ca href=\"\/products\/vitamin-b12-methylcobalamin-capsules\"\u003eVitamin B12 Methylcobalamin Capsules\u003c\/a\u003e, or \u003ca href=\"\/products\/tri-b12-vitamin-liquid\"\u003eTRI-B12 Liquid\u003c\/a\u003e for all three forms in one bottle. For a liquid adenosylcobalamin option see \u003ca href=\"\/products\/vitamin-b12-adenosylcobalamin-liquid\"\u003eVitamin B12 Adenosylcobalamin Liquid\u003c\/a\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e1000 mcg adenosylcobalamin per capsule\u003c\/strong\u003e (40000% NRV)\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eVegetarian capsule shell\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in the UK\u003c\/strong\u003e by Metabolics\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEach capsule provides 1000mcg of vitamin B12 as adenosylcobalamin, the mitochondrial form of B12 that is active as a cofactor for the enzyme methylmalonyl CoA mutase. This enzyme is essential for the metabolism of odd chain fatty acids and certain amino acids (valine, isoleucine, methionine, threonine) within the mitochondria for energy production. When adenosylcobalamin is insufficient, methylmalonic acid (MMA) accumulates, which is used clinically as a specific marker of functional B12 deficiency.\u003c\/p\u003e\u003cp\u003eAdenosylcobalamin is the less commonly supplemented of the two active B12 forms (the other being methylcobalamin), yet it is equally important. While methylcobalamin supports methylation in the cytoplasm, adenosylcobalamin supports energy production in the mitochondria. Symptoms of adenosylcobalamin deficiency include fatigue, muscle weakness and neurological symptoms, even when methylcobalamin levels are adequate. At 1000mcg per capsule, this provides a beneficial dose for those specifically targeting mitochondrial B12 function. The vegetarian capsule shell makes this suitable for most dietary requirements.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial energy\u003c\/strong\u003e production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhysical endurance\u003c\/strong\u003e and less fatigue\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive form\u003c\/strong\u003e no conversion needed\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eEach capsule contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e1000 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e40000%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003eCellulose, Hydroxypropyl Methylcellulose (capsule), Adenosylcobalamin.\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 capsule per day with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eTaking with a meal supports absorption. This product is specifically chosen when mitochondrial energy support is the primary goal, or when MMA levels are elevated on blood tests despite adequate methylcobalamin supplementation.\u003c\/p\u003e\u003cp\u003eFor comprehensive B12 coverage, this product can be paired with \u003ca href=\"\/products\/vitamin-b12-methylcobalamin-capsules\"\u003eVitamin B12 Methylcobalamin Capsules\u003c\/a\u003e to provide both active forms simultaneously, or \u003ca href=\"\/products\/tri-b12-vitamin-liquid\"\u003eTRI-B12 Liquid\u003c\/a\u003e can be used instead to provide all three forms (adenosylcobalamin, methylcobalamin and hydroxocobalamin) in a single product.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"Default Title","offer_id":47594985455890,"sku":"ADENO90C","price":23.28,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB12Adenosylcobalamin.jpg?v=1740698868"},{"product_id":"vitamin-b12-cyanocobalamin","title":"Vitamin B12 Cyanocobalamin","description":"\u003cp\u003e\u003cstrong\u003eMaintain healthy B12 levels with this standard form for general supplementation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eA liquid vitamin B12 providing 98mcg of cyanocobalamin per single drop in a purified water base. Cyanocobalamin is the synthetic, most stable form of B12 and the form used in the majority of clinical research on B12 supplementation. It requires conversion in the body to the two active forms (methylcobalamin and adenosylcobalamin) before it can participate in metabolic reactions.\u003c\/p\u003e\n\u003cp\u003eThe primary advantage of cyanocobalamin is its exceptional stability. Unlike methylcobalamin and adenosylcobalamin, which are light sensitive and can degrade in storage, cyanocobalamin maintains its potency reliably over time. It is also the most cost effective B12 form. For the majority of people who do not have impaired conversion pathways, cyanocobalamin is effectively converted to the active forms and provides the same functional benefit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHealthy B12 levels\u003c\/strong\u003e maintained\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy and blood cell\u003c\/strong\u003e production\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStable form\u003c\/strong\u003e for daily use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height: 1.25rem;\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e1 drop contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e98 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e3920%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003ePurified Water, Cyanocobalamin.\u003c\/p\u003e\n\u003cp\u003e1 serving = 1 drop | 1351 servings per 100ml\u003c\/p\u003e\n\u003cdiv style=\"height: 1.25rem;\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTake 1 drop per day in water with food.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTaking with a meal supports absorption. The drop can be added to water or taken directly. For those who know they have MTHFR variants or other methylation issues, the active forms (methylcobalamin, adenosylcobalamin or TRI B12) may be preferred, as they bypass the conversion step. For those without specific conversion concerns, cyanocobalamin is a reliable and stable choice.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"100ml","offer_id":50182864470290,"sku":"CYAN100T","price":22.68,"currency_code":"GBP","in_stock":true},{"title":"250ml","offer_id":50182864503058,"sku":"CYAN250T","price":30.0,"currency_code":"GBP","in_stock":true},{"title":"500ml","offer_id":50182864535826,"sku":"CYAN500T","price":54.73,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB12Cyanocobalamin_c7f42a87-364d-4dd1-b939-d3f05b2903cd.jpg?v=1740698761"},{"product_id":"vitamin-b12-hydroxocobalamin","title":"Vitamin B12 Hydroxocobalamin","description":"\u003cp\u003e\u003cstrong\u003eLiquid vitamin B12 as hydroxocobalamin, the form the body retains and converts as needed\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHydroxocobalamin only, no other B12 forms.\u003c\/strong\u003e This liquid contains hydroxocobalamin as its sole form of vitamin B12, with no methylcobalamin, adenosylcobalamin or cyanocobalamin, and no other ingredients beyond purified water. If you want an active form directly, see \u003ca href=\"\/products\/vitamin-b12-methylcobalamin-liquid\"\u003eVitamin B12 Methylcobalamin Liquid\u003c\/a\u003e or \u003ca href=\"\/products\/vitamin-b12-adenosylcobalamin-liquid\"\u003eVitamin B12 Adenosylcobalamin Liquid\u003c\/a\u003e, or \u003ca href=\"\/products\/tri-b12-vitamin-liquid\"\u003eTRI-B12 Liquid\u003c\/a\u003e for all three forms in one bottle.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e98 mcg hydroxocobalamin per drop\u003c\/strong\u003e (3920% NRV), 1 drop = 1 serving\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eAvailable in 100ml, 250ml and 500ml bottles\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan\u003c\/strong\u003e, gluten free, dairy free, nut free\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in the UK\u003c\/strong\u003e by Metabolics\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSublingual option\u003c\/strong\u003e: hold under the tongue for 30 seconds\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eA liquid vitamin B12 providing 98mcg of hydroxocobalamin per single drop in a purified water base. Hydroxocobalamin is the form of B12 that the body stores most efficiently and can convert to either of the two active forms (methylcobalamin or adenosylcobalamin) as needed. It has the longest retention time of any B12 form, meaning it is released slowly from tissue stores rather than being rapidly excreted like cyanocobalamin.\u003c\/p\u003e\u003cp\u003eHydroxocobalamin is the form the body retains longest and can convert into either active form as needed. That makes it a versatile everyday choice for those who would rather let the body direct the conversion, and for anyone who finds methylcobalamin overstimulating. It is naturally suited to vegetarians and vegans, who can find it harder to get enough B12 from diet alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWell-retained\u003c\/strong\u003e form, released slowly from stores\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBody converts\u003c\/strong\u003e to either active form as needed\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiquid drops\u003c\/strong\u003e, easy to take, suitable for vegans\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e1 drop contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e98 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e3920%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp class=\"u-text-midgrey\"\u003e* Nutrient Reference Value\u003c\/p\u003e\n\u003cp\u003ePurified Water, Hydroxocobalamin.\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 drop per day in water with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe drop can be taken in water, directly on the tongue or sublingually. Hydroxocobalamin's retention means it is a practical choice for those who want to build B12 stores steadily. Some people take 2 to 3 drops daily; if you think you may be low in B12, ask your GP for a blood test rather than self-treating.\u003c\/p\u003e\u003cp\u003eThis form is well suited to those who cannot tolerate methylcobalamin (which can feel overstimulating for some people with methylation sensitivities) and to anyone who would rather let the body direct the conversion.\u003c\/p\u003e\u003ch3\u003eFrequently asked questions\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eWhat is the difference between hydroxocobalamin and methylcobalamin?\u003c\/strong\u003e\u003cbr\u003eBoth are forms of vitamin B12. Hydroxocobalamin is retained longer and the body converts it into the active forms as needed; methylcobalamin is already an active form. Some people who find methylcobalamin overstimulating prefer hydroxocobalamin.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIs hydroxocobalamin better than cyanocobalamin?\u003c\/strong\u003e\u003cbr\u003eHydroxocobalamin is retained in the body longer than cyanocobalamin, which is why many people prefer it for daily use.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHow do I take B12 drops?\u003c\/strong\u003e\u003cbr\u003eOne drop daily in water, on the tongue, or held under the tongue, with food.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIs this suitable for vegans?\u003c\/strong\u003e\u003cbr\u003eYes. It contains only purified water and hydroxocobalamin.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"100ml","offer_id":50182868336914,"sku":"HYDX100T","price":20.59,"currency_code":"GBP","in_stock":true},{"title":"250ml","offer_id":50182868369682,"sku":"HYDX250T","price":41.71,"currency_code":"GBP","in_stock":true},{"title":"500ml","offer_id":50182868402450,"sku":"HYDX500T","price":73.36,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB12Hydroxocobalamin_7deef01d-1c37-4539-96a5-c84ca3cd7715.jpg?v=1740698659"},{"product_id":"vitamin-b12-methylcobalamin-liquid","title":"Vitamin B12 Methylcobalamin Liquid","description":"\u003cp\u003e\u003cstrong\u003eAbsorb active B12 rapidly with sublingual methylcobalamin delivery\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethylcobalamin only, no other B12 forms.\u003c\/strong\u003e This liquid contains methylcobalamin as its sole form of vitamin B12, with no adenosylcobalamin, cyanocobalamin or hydroxocobalamin, and no other ingredients beyond purified water. For the mitochondrial form see \u003ca href=\"\/products\/vitamin-b12-adenosylcobalamin-liquid\"\u003eVitamin B12 Adenosylcobalamin Liquid\u003c\/a\u003e, or \u003ca href=\"\/products\/tri-b12-vitamin-liquid\"\u003eTRI-B12 Liquid\u003c\/a\u003e for all three forms in one bottle.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e86.5 mcg methylcobalamin per drop\u003c\/strong\u003e (3460% NRV), 1 drop = 1 serving\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003e1538 servings per 100ml bottle\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cstrong\u003eAvailable in 100ml, 250ml and 500ml bottles\u003c\/strong\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVegan\u003c\/strong\u003e, gluten free, dairy free, nut free\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMade in the UK\u003c\/strong\u003e by Metabolics\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSublingual option\u003c\/strong\u003e: hold under the tongue for 30 seconds\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eA liquid vitamin B12 providing 86.5mcg of methylcobalamin per single drop in a purified water base. Methylcobalamin is the active B12 form used in the cytoplasm for methylation reactions, serving as a cofactor for methionine synthase (homocysteine clearance, methylation cycle). The liquid format enables precise dose titration, which is particularly valuable with methylcobalamin because some individuals are sensitive to this form and need to start at lower doses.\u003c\/p\u003e\u003cp\u003eThe sublingual option (holding under the tongue) bypasses digestive absorption entirely, which is important for the significant percentage of the population with B12 absorption issues (estimated at 10 to 15% of those over 60). The purified water base contains no additives, preservatives or flavourings. The bottle provides 1538 servings per 100ml, making this one of the most economical B12 supplements available on a per serving basis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid absorption\u003c\/strong\u003e under the tongue\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNerve health\u003c\/strong\u003e and cognition\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eActive methyl B12\u003c\/strong\u003e for immediate use\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e1 drop contains:\u003c\/th\u003e\n\u003cth\u003e\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e86.5 mcg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd align=\"right\"\u003e3460%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cp\u003ePurified Water, Methylcobalamin\u003c\/p\u003e\n\u003cp\u003e1 serving = 1 drop | 1538 servings per 100ml\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 1 drop per day in water with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eFor sublingual absorption, place 1 drop under the tongue and hold for 30 seconds before swallowing. For those with methylation sensitivities, start with 1 drop every other day and increase to daily based on tolerance.\u003c\/p\u003e\u003cp\u003eThe liquid format is the preferred starting point for those new to methylcobalamin supplementation, as the 86.5mcg dose allows a gentler introduction than the 1000mcg capsule. Once tolerance is established, some individuals may prefer to switch to the capsule for the higher dose. For those who tolerate it well but want comprehensive B12 coverage, pairing with the Adenosylcobalamin Liquid provides both active forms.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"100ml","offer_id":50182928990482,"sku":"METH0100T","price":22.68,"currency_code":"GBP","in_stock":true},{"title":"250ml","offer_id":50182929023250,"sku":"METH0250T","price":31.92,"currency_code":"GBP","in_stock":true},{"title":"500ml","offer_id":50182929056018,"sku":"METH0500T","price":54.73,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/VitaminB12MethylcobalaminLiquid_991292fc-afa4-45b5-8b72-cf4bfd4c9f18.jpg?v=1740698579"},{"product_id":"tri-b12-vitamin-liquid","title":"TRI-B12 Vitamin - Liquid","description":"\u003cp\u003e\u003cstrong\u003eMaximise B12 absorption with all three active cobalamin forms in one liquid\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAll three active B12 forms in one bottle.\u003c\/strong\u003e This liquid provides adenosylcobalamin, methylcobalamin and hydroxocobalamin together, with no cyanocobalamin. For a single form at a higher dose see \u003ca href=\"\/products\/vitamin-b12-methylcobalamin-liquid\"\u003eVitamin B12 Methylcobalamin Liquid\u003c\/a\u003e, \u003ca href=\"\/products\/vitamin-b12-adenosylcobalamin-liquid\"\u003eVitamin B12 Adenosylcobalamin Liquid\u003c\/a\u003e or \u003ca href=\"\/products\/vitamin-b12-hydroxocobalamin\"\u003eVitamin B12 Hydroxocobalamin\u003c\/a\u003e.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e300 mcg total B12 per 10 drop serving\u003c\/strong\u003e (12000% NRV)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100 mcg adenosylcobalamin, 100 mcg methylcobalamin, 100 mcg hydroxocobalamin\u003c\/strong\u003e per serving\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSublingual option\u003c\/strong\u003e: hold under the tongue before swallowing\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eA unique liquid vitamin B12 providing all three bioactive forms of B12 in a single product: 100mcg adenosylcobalamin, 100mcg methylcobalamin and 100mcg hydroxocobalamin per 10 drop serving (300mcg total, 12000% NRV). Each form of B12 serves a distinct metabolic function, and providing all three ensures comprehensive B12 activity regardless of individual genetic variations or metabolic needs.\u003c\/p\u003e\u003cp\u003eMethylcobalamin is the form active in the cytoplasm, where it serves as a cofactor for methionine synthase (methylation cycle, homocysteine clearance). Adenosylcobalamin is the form active in the mitochondria, where it supports the enzyme methylmalonyl CoA mutase (energy production from fats and amino acids). Hydroxocobalamin is the form the body stores most efficiently and can convert to either active form as needed; it also has specific evidence for nitric oxide scavenging and cyanide detoxification. The liquid format allows flexible dosing and is ideal for those who have difficulty absorbing B12 from capsules due to low stomach acid, intrinsic factor deficiency or digestive conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey benefits:\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAll three B12\u003c\/strong\u003e forms in one dose\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSublingual delivery\u003c\/strong\u003e for rapid uptake\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy and nerve\u003c\/strong\u003e function support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e10 drops contain\u003c\/th\u003e\n\u003cth\u003eAmount\u003c\/th\u003e\n\u003cth\u003e%NRV*\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eVitamin B12\u003c\/td\u003e\n\u003ctd\u003e300 µg\u003c\/td\u003e\n\u003ctd\u003e12000%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e(as adenosylcobalamin 100 µg, methylcobalamin 100 µg, hydroxocobalamin 100 µg)\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e† Nutrient Reference Value (NRV*) not established\u003c\/p\u003e\n\u003cdiv style=\"height:1.25rem\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTake 10 drops daily in water with food.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe drops can be added to a glass of water, juice or taken directly under the tongue for sublingual absorption (which bypasses the digestive system and is particularly useful for those with B12 absorption issues). Taking with food supports general absorption for those without specific absorption concerns.\u003c\/p\u003e\u003cp\u003eThis product is the most comprehensive B12 supplement in the range. For those who know they need a specific form (methylcobalamin for methylation, adenosylcobalamin for mitochondrial energy), the individual B12 products provide higher single form doses. TRI-B12 is the best choice when broad B12 coverage is the goal or when the specific form needed is unknown.\u003c\/p\u003e","brand":"Metabolics","offers":[{"title":"100ml","offer_id":50303277302034,"sku":"TRIB12_100ML","price":24.95,"currency_code":"GBP","in_stock":true},{"title":"250ml","offer_id":50303277334802,"sku":"TRIB12_250ML","price":31.95,"currency_code":"GBP","in_stock":true},{"title":"500ml","offer_id":50303277367570,"sku":"TRIB12_500ML","price":39.95,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0787\/9462\/1202\/files\/TRIB12Liquidnoml.jpg?v=1740697977"}],"url":"https:\/\/nutritailor.co.uk\/collections\/b-vitamin-supplements.oembed","provider":"Nutri Tailor","version":"1.0","type":"link"}