5-Hydroxytryptophan (5-HTP)

5-HTP (5-Hydroxytryptophan) is a naturally occurring amino acid derived from the seeds of the Griffonia simplicifolia plant. It is the direct precursor to serotonin, the neurotransmitter that regulates mood, appetite, sleep and emotional wellbeing.

Each capsule provides 50mg of 5-HTP alongside 2.3mg of vitamin B6 in its active pyridoxal 5 phosphate (P5P) form. B6 is a required cofactor for the conversion of 5-HTP into serotonin, so including it ensures the conversion pathway has what it needs to function efficiently.

5-HTP is commonly recommended for low mood, anxiety, difficulty sleeping, and carbohydrate or sugar cravings. Because serotonin is also converted into melatonin (the sleep hormone), supporting serotonin levels can have downstream benefits for sleep quality.

Unlike SSRIs, 5-HTP provides the raw material for serotonin production rather than preventing its reuptake. This makes it a gentler approach, though it should not be combined with SSRI or SNRI medications without medical guidance due to the risk of serotonin syndrome.

Take 1 capsule per day with food.

For mood support, morning dosing works well. For sleep support, taking it in the evening 30 to 60 minutes before bed allows serotonin to convert to melatonin overnight.

If you are taking any antidepressant medication, consult your healthcare practitioner before using 5-HTP. Do not combine with SSRIs, SNRIs or MAOIs without medical supervision.