Methylfolate Capsules

Active folate, ready for the body to use without conversion.

  • Helps reduce tiredness and fatigue
  • Supports normal blood formation
  • Contributes to a healthy immune system
60 capsules
60 day supply

per day £0.39 per capsule

Guaranteed additive free
Highest purity
Practitioner grade
Free UK delivery on 2 or more items 14 day returns

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Methylfolate, or 5-MTHF, is folate in the form the body uses directly. It is supplied here as calcium L-methylfolate.

Folate is needed for making blood, for the immune system and for psychological function, and it contributes to the reduction of tiredness and fatigue. It does not need converting by the body, which matters for people who convert folic acid poorly.

Each capsule provides a high dose of methylfolate with no folic acid, no fillers and no binders, in a vegetable capsule suitable for vegans. It is often chosen by people who have been advised to take the active form.

Each capsule contains:%NRV*
Folate1000 mcg500%

† Nutrient Reference Value (NRV*) not established

Cellulose, Hydroxypropyl Methylcellulose (capsule), Calcium L-Methyl Folate.

Take 1 capsule per day with food.

This product is suitable for anyone who needs folate supplementation but wants to bypass the conversion step required by folic acid. It is particularly relevant for those who know they carry MTHFR variants (C677T or A1298C), those with elevated homocysteine, women planning pregnancy, and those using folate for mood or methylation support.

If taking alongside vitamin B12, ensure the B12 is also in its active form (methylcobalamin or adenosylcobalamin) for consistent methylation support. Folate and B12 work together in the methylation cycle and should ideally be supplemented as a pair when either is taken at therapeutic doses.

  • Suitable for men.

  • Suitable for women.

  • Consult your healthcare practitioner before use if pregnant or breastfeeding.

  • Suitable for vegetarians.

  • Suitable for vegans.

  • No gluten containing ingredients.

  • No nut containing ingredients.

  • No dairy containing ingredients.

If you are taking prescribed medicines or under medical supervision, consult your healthcare practitioner before use.

Store in a cool dry place.

Keep out of reach of children.

This information is not a substitute for advice from a healthcare practitioner.

This product should not be used as a substitute for a varied diet.

Once opened, consume within 3 months.

UK delivery is free when you order 2 or more items. A single item goes by Royal Mail Tracked 48 for £3.95. With 3 or more items, Tracked 24 is free. With 4 or more items, Special Delivery is free. Special Delivery arrives the next working day if you order before 2pm.

Delivery and worldwide shipping options are shown at checkout, with duties and taxes included.

Unopened items in their original packaging can be returned within 14 days of delivery.

Methylfolate Capsules
Quality manufacturing

Quality promise

Why clinical grade matters

  • GMP certified, pharmaceutical grade manufacturing
  • Made in UK cleanroom facilities, ISO 9001 & ISO 14001 accredited
  • No fillers, binders or additives, only active ingredients
  • Fully traceable from raw material to finished product
  • Non-GM, non-irradiated, 100% green energy manufacturing
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Frequently asked questions

What is the difference between methylfolate and folic acid?

Methylfolate (5-MTHF) is the bioactive form the body uses directly. Folic acid is synthetic and must be converted by the MTHFR enzyme, which runs slowly in the estimated 30 to 40% of people carrying MTHFR gene variants.

How much folate is in each capsule?

1000mcg (500% NRV) as calcium L-methylfolate. One capsule daily, 60 per pot.

Who is methylfolate for?

Anyone with a known MTHFR variant, anyone who has not noticed benefit from folic acid, and anyone who prefers the active form the body uses without conversion.

What does methylated mean?

Methylated B vitamins are pre-activated forms your body can use immediately. Important for those with MTHFR gene variations.

Can B vitamins make me feel overstimulated?

Some people are sensitive to certain B vitamins. Start with a lower dose and take with food if you notice you feel overstimulated.

Is this vegan, and is it free from gluten, dairy and nuts?

Yes, it is vegan. It is free from gluten, dairy and nuts. The full ingredient list and allergen information are on the label image and in the Information and Allergens tab above.

Why capsules rather than tablets?

Tablets need binders, fillers and a coating to hold their shape. A capsule is a cellulose shell around the powder, so it carries no binders and breaks down quickly once swallowed.

Methylfolate Capsules

Methylfolate Capsules

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