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Supplements for gut health

Probiotics, digestive enzymes, prebiotic fibre, L-glutamine and magnesium citrate: what each is for and how long the trials took.

  • 10 billion CFU per capsule
  • Multi strain blend 415 mg
  • Capsule swallowed whole
Combocillus Probiotic Powder

Combocillus Probiotic Powder

  • 10 billion CFU per capsule
  • Multi strain blend 415 mg
  • Capsule swallowed whole
£32.88
90 day supply

0.00 per day

  • 10 billion CFU per serving
  • Single strain Lactobacillus rhamnosus
  • Powder dosed by the scoop
Lactobacillus Rhamnosus Powder

Lactobacillus Rhamnosus Powder

  • 10 billion CFU per serving
  • Single strain Lactobacillus rhamnosus
  • Powder dosed by the scoop
£44.52
200 day supply

0.00 per day

  • Protease, amylase and peptidase
  • Taken with meals breaks down protein, starch and fat
  • Broad spectrum enzyme blend
Enzymase Digestive Enzyme Complex

Enzymase Digestive Enzyme Complex

  • Protease, amylase and peptidase
  • Taken with meals breaks down protein, starch and fat
  • Broad spectrum enzyme blend
£22.02
30 day supply

0.00 per day

  • Psyllium and inulin prebiotic fibre
  • Probiotic blend included
  • Powder 250 g
Colon Support Formula Capsules

Colon Support Formula Capsules

  • Psyllium and inulin prebiotic fibre
  • Probiotic blend included
  • Powder 250 g
£31.28
50 day supply

0.00 per day

  • 400 mg L-glutamine per capsule
  • Single amino acid nothing added
  • 100 capsules per pot
L-Glutamine Capsules

L-Glutamine Capsules

  • 400 mg L-glutamine per capsule
  • Single amino acid nothing added
  • 100 capsules per pot
£23.28
16 day supply

0.00 per day

  • 85 mg magnesium per capsule
  • Normal muscle function magnesium contributes
  • Less tiredness magnesium contributes
Magnesium Citrate

Magnesium Citrate

  • 85 mg magnesium per capsule
  • Normal muscle function magnesium contributes
  • Less tiredness magnesium contributes
£22.08
22 day supply

0.00 per day

How to choose a gut health supplement

Gut health is where blends are sold hardest and where the single ingredients are easiest to judge one at a time.

Why these

Combocillus Probiotic Powder: Multi strain probiotic capsules at 10 billion CFU; the benefit in trials shows up over about four weeks.

Lactobacillus Rhamnosus Powder: One well-researched strain as a powder, dosed by the scoop.

Enzymase Digestive Enzyme Complex: Digestive enzymes taken with meals.

Colon Support Formula Capsules: Prebiotic fibre with a probiotic blend, increased gradually.

L-Glutamine Capsules: L-glutamine, the amino acid most used by the gut lining.

Magnesium Citrate: For regularity; the bowel effect arrives within a day.

What to skip

Anything called a cleanse or a detox. Persistent bloating, a change in bowel habit, or blood in the stool needs a GP, not a supplement.

Read the evidence

How long do probiotics take to work? · Which probiotic should you buy?

If you take prescribed medicines, are pregnant or breastfeeding, or have a diagnosed condition, talk to your GP or pharmacist first. Not sure which fits? Ask Nutri365, the Nutri Tailor AI health expert, which checks for interactions and contraindications.

Written by Nutri Tailor from the Health Reference Library. Last checked 6 September 2026. General information, not personal advice.

Common questions

How long do probiotics take to work?

It depends on why you are taking them. Alongside antibiotics the benefit shows during the course; for general gut symptoms the trials mostly measured at four weeks or more.

Should I take digestive enzymes with every meal?

They are taken with the meals that cause trouble, not every meal. The label gives the directions.

Do I need a probiotic and a prebiotic?

Not necessarily. Prebiotic fibre feeds the bacteria you already have; a probiotic adds specific strains. Many people start with one and judge over a month.

Written by Nutri Tailor from the Health Reference Library. Last checked 6 September 2026. General information, not personal advice.