SAMe Liquid

S-adenosyl methionine as a liquid, the form that keeps its potency.

  • Supports normal homocysteine metabolism through methylation
  • SAMe in purified water, nothing else
  • Taken by the 5 ml spoonful

£23.52

100ml
20 day supply

£1.18 per day

Guaranteed additive free
Highest purity
Practitioner grade
Free Standard UK delivery over £35.00 30 day returns

★★★★★ "I won't go back to high street supplements. The difference in quality is something you can actually feel." Susie

SAMe Liquid gives you S-adenosyl-L-methionine in purified water, the form that keeps its potency. Each 5ml spoonful provides 50mg of SAMe and you take one spoonful a day in water, with food. One 100ml bottle holds 20 servings.

Benefits of taking SAMe

SAMe is a compound the body makes from methionine and ATP and uses as its main methyl donor, handing a methyl group to more than a hundred reactions, including the pathway that processes homocysteine and the ones that make neurotransmitters. It is unstable as a powder, which is why most products are coated tablets. A water based liquid keeps its potency in the fridge and lets the amount start low.

  • Each spoonful gives a fixed 50mg, a low starting amount that a practitioner can build on.
  • Nothing else is in the bottle apart from purified water.
  • Potency holds in the fridge, where a powder would break down.
  • Swallowing is easy, because it is a liquid rather than a coated tablet.

Who benefits

SAMe Liquid is most useful for:

  • People whose practitioner has suggested SAMe within a methylation routine alongside B12, folate and B6.
  • Anyone who wants a low starting amount they can adjust by the spoonful.
  • Those who prefer a liquid to a coated tablet.

If you are building a methylation routine, Vitamin B12 Methylcobalamin Drops and L-Methylfolate 5-MTHF Capsules are the two it is most often taken with.

What is in it

Each 5ml spoonful provides 50mg of S-adenosyl-L-methionine. The only other ingredient is purified water. There is no authorised health claim for SAMe, so Nutri Tailor describes it by what it contains.

How to take it

Take one 5ml spoonful a day mixed into water, with food. Keep the bottle in the fridge once it is open.

Diet and allergens

The liquid is suitable for vegans and vegetarians. It is free from gluten, dairy and nuts.

Quality

The liquid is made in the UK in a GMP certified cleanroom facility accredited to ISO 9001 and ISO 14001. Every batch is traceable from raw material to finished product. Like every supplement Nutri Tailor stocks, it is practitioner grade and guaranteed additive free.

Common questions

What does SAMe do in the body?
It is the body's main methyl donor, handing a methyl group to more than a hundred reactions, including the step that processes homocysteine and the ones that make neurotransmitters.

How much SAMe should I take a day?
One 5ml spoonful, which gives you 50mg. A 100ml bottle lasts 20 days at that amount. If a practitioner has advised more, follow their advice.

When is the best time to take it?
With food, at any time of day. Mix the spoonful into water and keep the bottle refrigerated once opened.

Why is SAMe sold as a liquid?
SAMe is unstable as a powder, which is why most products are coated tablets. A water based liquid keeps its potency when refrigerated and lets the amount start low.

Can I take it with other supplements?
Yes. It is usually taken within a methylation routine alongside Vitamin B12 Methylcobalamin Drops, L-Methylfolate 5-MTHF Capsules and vitamin B6.

Does SAMe have side effects?
It is well tolerated at one spoonful a day with food. If you take prescribed tablets, are pregnant or breastfeeding, speak to your GP or pharmacist first.

Delivery and returns

Order before 2pm Monday to Friday and your bottle is dispatched the same day from the UK. Standard UK delivery by Royal Mail Tracked 48 takes 2 to 4 working days and costs £3.35, or it is free when you spend £35 or more. Faster delivery is available at checkout. Nutri Tailor also ships worldwide, with duties and taxes shown before you pay. You can return unopened items within 30 days of delivery. New customers get 10% off their first order.

Why Nutri Tailor

Nutri Tailor is rated 4.6 out of 5, "Excellent", on Trustpilot. Every supplement is chosen by experienced nutritional therapists. Kasia Key, Registered Associate Nutritionist, says: "I use Nutri Tailor for myself and my clients because you can be certain that their supplements are industry leading quality."

Sources

The information on this page comes from the product label.

5ml spoonful contains:Amount%NRV*
S-Adenosyl-L-Methionine50 mg†

† Nutrient Reference Value (NRV*) not established

Purified Water, S- Adenosyl-L-Methionine.

Take 1 x 5ml spoonful per day mixed into water, with food.

Take it as the label directs. If you take prescribed tablets, are pregnant or breastfeeding, or have a diagnosed condition, talk to your GP or pharmacist first.

  • Suitable for men.

  • Suitable for women.

  • Consult your healthcare practitioner before use if pregnant or breastfeeding.

  • Suitable for vegetarians.

  • Suitable for vegans.

  • No gluten containing ingredients.

  • No nut containing ingredients.

  • No dairy containing ingredients.

If you are taking prescribed medicines or under medical supervision, consult your healthcare practitioner before use.

Store in a cool dry place.

Keep out of reach of children.

This information is not a substitute for advice from a healthcare practitioner.

This product should not be used as a substitute for a varied diet.

Once opened, consume within 3 months.

UK Standard Delivery (Royal Mail Tracked 48, 2 to 4 working days) is £3.35, or free on orders of £35 or more. Express Delivery (Tracked 24, 1 to 2 working days) is £5.65, free on orders of £60 or more. Next Day Delivery (Royal Mail Special Delivery) is £8.50, free on orders of £100 or more; order before 2pm on a working day for next-working-day arrival. We dispatch Monday to Friday.

Delivery and worldwide shipping options are shown at checkout, with duties and taxes included.

Unopened items in their original packaging can be returned within 30 days of delivery.

New customers get 10% off their first order.

SAMe Liquid
Quality manufacturing

Quality promise

Why clinical grade matters

  • ✓ GMP certified, pharmaceutical grade manufacturing
  • ✓ Made in UK cleanroom facilities, ISO 9001 & ISO 14001 accredited
  • ✓ No fillers, binders or additives, only active ingredients
  • ✓ Fully traceable from raw material to finished product
  • ✓ Non-GM, non-irradiated, 100% green energy manufacturing

Evidence

What the research shows

Our Health Reference Library is an ever-growing collection of peer-reviewed research and health guidance.

Research and routine
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Why nutri Tailor?

Nutri Tailor makes supplements make sense, but what does this mean?

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This is where Nutri Tailor comes in as it is the only platform to combine expert advice with showing you which supplements are the highest quality in the most effective combination.

Kasia Key

Registered Associate Nutritionist (ANutr), MSc Nutritional Medicine

Florence de Walden, Nutritional Therapist
I use Nutri Tailor for myself and my clients because you can be certain that their supplements are industry leading quality.

Florence de Walden

Nutritional Therapist, BSc (Hons) DipNT mBANT

Frequently asked questions

What does SAMe do in the body?

SAMe is the body's main methyl donor. It hands a methyl group to more than a hundred reactions, including the pathway that processes homocysteine.

When should I take SAMe?

One 5 ml spoonful a day in water, with food. Keep the bottle refrigerated once opened.

Can I take this alongside other supplements?

SAMe is usually taken within a methylation routine alongside B12, folate and B6. If you take prescribed tablets, ask your GP or pharmacist first.

Why is SAMe sold as a liquid?

SAMe is unstable as a powder, which is why most products are coated tablets. A water-based liquid keeps its potency when refrigerated and lets the dose start low.

Who is SAMe best for?

People whose practitioner has suggested SAMe within a methylation routine alongside B12, folate and B6, people who want a low starting dose, and people who prefer a liquid to a coated tablet. Anyone on prescribed tablets speaks to a GP or pharmacist before starting. There is no authorised health claim for SAMe.

What is SAMe?

S-adenosyl-L-methionine, the molecule the body makes from methionine and ATP and uses as its main methyl donor. It is unstable, so most products are coated tablets; this is a water-based liquid, 50 mg per 5ml spoonful, kept refrigerated once opened.

Why drops rather than tablets?

Drops let the amount be adjusted one drop at a time, and they suit anyone who cannot swallow tablets. Tablets need binders and a coating to hold their shape; this liquid contains only the active ingredient and its carrier.

SAMe Liquid

SAMe Liquid

£23.52