S-adenosyl methionine as a liquid, the form that keeps its potency.
£23.52
£1.18 per day
★★★★★ "I won't go back to high street supplements. The difference in quality is something you can actually feel." Susie
SAMe Liquid gives you S-adenosyl-L-methionine in purified water, the form that keeps its potency. Each 5ml spoonful provides 50mg of SAMe and you take one spoonful a day in water, with food. One 100ml bottle holds 20 servings.
SAMe is a compound the body makes from methionine and ATP and uses as its main methyl donor, handing a methyl group to more than a hundred reactions, including the pathway that processes homocysteine and the ones that make neurotransmitters. It is unstable as a powder, which is why most products are coated tablets. A water based liquid keeps its potency in the fridge and lets the amount start low.
SAMe Liquid is most useful for:
If you are building a methylation routine, Vitamin B12 Methylcobalamin Drops and L-Methylfolate 5-MTHF Capsules are the two it is most often taken with.
Each 5ml spoonful provides 50mg of S-adenosyl-L-methionine. The only other ingredient is purified water. There is no authorised health claim for SAMe, so Nutri Tailor describes it by what it contains.
Take one 5ml spoonful a day mixed into water, with food. Keep the bottle in the fridge once it is open.
The liquid is suitable for vegans and vegetarians. It is free from gluten, dairy and nuts.
The liquid is made in the UK in a GMP certified cleanroom facility accredited to ISO 9001 and ISO 14001. Every batch is traceable from raw material to finished product. Like every supplement Nutri Tailor stocks, it is practitioner grade and guaranteed additive free.
What does SAMe do in the body?
It is the body's main methyl donor, handing a methyl group to more than a hundred reactions, including the step that processes homocysteine and the ones that make neurotransmitters.
How much SAMe should I take a day?
One 5ml spoonful, which gives you 50mg. A 100ml bottle lasts 20 days at that amount. If a practitioner has advised more, follow their advice.
When is the best time to take it?
With food, at any time of day. Mix the spoonful into water and keep the bottle refrigerated once opened.
Why is SAMe sold as a liquid?
SAMe is unstable as a powder, which is why most products are coated tablets. A water based liquid keeps its potency when refrigerated and lets the amount start low.
Can I take it with other supplements?
Yes. It is usually taken within a methylation routine alongside Vitamin B12 Methylcobalamin Drops, L-Methylfolate 5-MTHF Capsules and vitamin B6.
Does SAMe have side effects?
It is well tolerated at one spoonful a day with food. If you take prescribed tablets, are pregnant or breastfeeding, speak to your GP or pharmacist first.
Order before 2pm Monday to Friday and your bottle is dispatched the same day from the UK. Standard UK delivery by Royal Mail Tracked 48 takes 2 to 4 working days and costs £3.35, or it is free when you spend £35 or more. Faster delivery is available at checkout. Nutri Tailor also ships worldwide, with duties and taxes shown before you pay. You can return unopened items within 30 days of delivery. New customers get 10% off their first order.
Nutri Tailor is rated 4.6 out of 5, "Excellent", on Trustpilot. Every supplement is chosen by experienced nutritional therapists. Kasia Key, Registered Associate Nutritionist, says: "I use Nutri Tailor for myself and my clients because you can be certain that their supplements are industry leading quality."
The information on this page comes from the product label.
| 5ml spoonful contains: | Amount | %NRV* |
|---|---|---|
| S-Adenosyl-L-Methionine | 50 mg | † |
† Nutrient Reference Value (NRV*) not established
Suitable for men.
Suitable for women.
Consult your healthcare practitioner before use if pregnant or breastfeeding.
Suitable for vegetarians.
Suitable for vegans.
No gluten containing ingredients.
No nut containing ingredients.
No dairy containing ingredients.
If you are taking prescribed medicines or under medical supervision, consult your healthcare practitioner before use.
Store in a cool dry place.
Keep out of reach of children.
This information is not a substitute for advice from a healthcare practitioner.
This product should not be used as a substitute for a varied diet.
Once opened, consume within 3 months.
UK Standard Delivery (Royal Mail Tracked 48, 2 to 4 working days) is £3.35, or free on orders of £35 or more. Express Delivery (Tracked 24, 1 to 2 working days) is £5.65, free on orders of £60 or more. Next Day Delivery (Royal Mail Special Delivery) is £8.50, free on orders of £100 or more; order before 2pm on a working day for next-working-day arrival. We dispatch Monday to Friday.
Delivery and worldwide shipping options are shown at checkout, with duties and taxes included.
Unopened items in their original packaging can be returned within 30 days of delivery.
New customers get 10% off their first order.

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SAMe is the body's main methyl donor. It hands a methyl group to more than a hundred reactions, including the pathway that processes homocysteine.
One 5 ml spoonful a day in water, with food. Keep the bottle refrigerated once opened.
SAMe is usually taken within a methylation routine alongside B12, folate and B6. If you take prescribed tablets, ask your GP or pharmacist first.
SAMe is unstable as a powder, which is why most products are coated tablets. A water-based liquid keeps its potency when refrigerated and lets the dose start low.
People whose practitioner has suggested SAMe within a methylation routine alongside B12, folate and B6, people who want a low starting dose, and people who prefer a liquid to a coated tablet. Anyone on prescribed tablets speaks to a GP or pharmacist before starting. There is no authorised health claim for SAMe.
S-adenosyl-L-methionine, the molecule the body makes from methionine and ATP and uses as its main methyl donor. It is unstable, so most products are coated tablets; this is a water-based liquid, 50 mg per 5ml spoonful, kept refrigerated once opened.
Drops let the amount be adjusted one drop at a time, and they suit anyone who cannot swallow tablets. Tablets need binders and a coating to hold their shape; this liquid contains only the active ingredient and its carrier.
