B12 and Folate

Support energy, mood and red blood cell production with active B12 and folate

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  • More energy and less tiredness
  • Healthy blood cells and oxygen delivery
  • Active forms for direct cellular use
90 capsules
90 day supply

per day

Guaranteed additive free
Highest purity
Therapeutically effective

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Have questions about B12 and Folate?

"I'm pregnant. Is this the right folate for me or do I need something specific?"

"My homocysteine is high. Will this help bring it down?"

"I already take a B complex. Do I still need this on top?"

Get tailored guidance from Nutri365, your personal AI health expert.

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B12 and Folate provides high dose methylated forms of two of the most commonly deficient B vitamins in a single capsule. Each capsule delivers 1000mcg of folate as calcium L-methylfolate and 1000mcg of vitamin B12 as methylcobalamin.

These two nutrients work closely together in the methylation cycle, which governs DNA synthesis, red blood cell production, nerve function and homocysteine metabolism. Deficiency in either can cause fatigue, brain fog, low mood, nerve symptoms and anaemia.

Both are provided in their active methylated forms, which is particularly important for the estimated 30 to 40% of people who carry MTHFR gene variants that impair the conversion of folic acid and cyanocobalamin into their usable forms. Methylfolate and methylcobalamin bypass this conversion entirely.

B12 deficiency is common in vegetarians, vegans, older adults and anyone taking metformin or proton pump inhibitors. Folate requirements increase during pregnancy, preconception and in anyone with elevated homocysteine levels.

Take 1 capsule per day with food.

One capsule provides the full therapeutic dose. Taking with any meal improves tolerability.

If you are taking this to correct a known deficiency, your practitioner may recommend a higher dose for the initial loading period. Retest B12 and folate levels after 8 to 12 weeks to confirm the response.

Each capsule contains: %NRV*
Folate 1000 mcg 500%
Vitamin B12 1000 mcg 40000%

† Nutrient Reference Value (NRV*) not established

Cellulose, Hydroxypropyl Methylcellulose (capsule), Calcium L Methyl Folate, Methylcobalamin.

Recommended dose: 1 capsule per day with food

  • Suitable for men.

  • Suitable for women.

  • Suitable for people under sixteen years of age.

  • If pregnant or breastfeeding consult your healthcare professional before purchasing and consuming this product.

  • Suitable for vegetarians.

  • Suitable for vegans.

  • No gluten containing ingredients.

  • No nut containing ingredients.

  • No dairy containing ingredients.

If you are taking medication consult your prescribing physician before purchasing and consuming supplements.

Store in a cool dry place.

Keep out of reach of children.

Information displayed does not constitute medical advice.

This product should not be used as a substitute for a varied diet.

Once opened, consume within 3 months.

B12 and Folate
Quality manufacturing

Quality promise

Why clinical grade matters

  • GMP certified, pharmaceutical grade manufacturing
  • Made in UK cleanroom facilities, ISO 9001 & ISO 14001 accredited
  • No fillers, binders or additives — only active ingredients
  • Fully traceable from raw material to finished product
  • Non-GM, non-irradiated, 100% green energy manufacturing
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Registered Associate Nutritionist (ANutr), MSc Nutritional Medicine

Frequently asked questions

Why take B12 and Folate?

B12 and Folate supports energy production, nervous system function, and stress resilience.

When should I take B vitamins?

Take in the morning with food to support energy throughout the day.

What are signs of B vitamin deficiency?

Common signs include fatigue, brain fog, mood changes, and numbness.

What does methylated mean?

Methylated B vitamins are pre-activated forms your body can use immediately. Important for those with MTHFR gene variations.

Can B vitamins cause anxiety?

Some people are sensitive to certain B vitamins. Start with a lower dose and take with food if you notice overstimulation.

Why do B vitamins turn urine yellow?

Riboflavin (B2) causes bright yellow urine. This is harmless and shows the vitamins are being processed.

B12 and Folate

B12 and Folate

$38.00