Vitamin B12 drops in each of the forms the body uses, made in the UK, in 100 ml, 250 ml and 500 ml bottles. Each bottle contains the B12 and purified water and nothing else: no flavouring, no sweetener, no alcohol, no preservative, and every one is vegan.
One drop is one serving. Hydroxocobalamin and cyanocobalamin provide 98 mcg of vitamin B12 per drop, methylcobalamin 86.5 mcg and adenosylcobalamin 76 mcg, so a 100 ml bottle holds between 1,350 and 1,750 servings. Tri-B12 is the exception: ten drops provide 300 mcg, 100 mcg each of methylcobalamin, adenosylcobalamin and hydroxocobalamin, about 166 servings a bottle. The drops are taken in water with food, or held under the tongue; published research finds the same result either way.
Which form to choose is a question of form, not of how much gets in. Methylcobalamin and adenosylcobalamin are the two forms enzymes use directly, one in the cell fluid and one in the mitochondria. Hydroxocobalamin is the stored form, kept in the body for longest and converted as enzymes need it. Cyanocobalamin is the stable form in most tablets and fortified foods, converted by the body into the active forms. Tri-B12 gives the three active forms together. Each product page sets out that form's questions and answers, with the sources.
Vitamin B12 contributes to normal energy-yielding metabolism, to the normal function of the nervous system and the immune system, to normal red blood cell formation and to the reduction of tiredness and fatigue. Anyone who thinks they may be low in B12 should ask a GP for a blood test before self-treating.
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