Vitamin B12 Hydroxocobalamin

Support sustained B12 levels and detoxification with this slow release form

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  • Sustained B12 release over time
  • Detox support and cyanide clearance
  • Clinical form for lasting effect
100ml
1351 day supply

per day

Guaranteed additive free
Highest purity
Therapeutically effective
100ml
250ml
500ml

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Have questions about Vitamin B12 Hydroxocobalamin?

"My practitioner recommended hydroxocobalamin specifically. Why this form over the others?"

"I can't tolerate methylcobalamin. Would this be a better option?"

"I've had B12 injections before. How does the liquid compare?"

Get tailored guidance from Nutri365, your personal AI health expert.

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A liquid vitamin B12 providing 98mcg of hydroxocobalamin per single drop in a purified water base. Hydroxocobalamin is the form of B12 that the body stores most efficiently and can convert to either of the two active forms (methylcobalamin or adenosylcobalamin) as needed. It has the longest retention time of any B12 form, meaning it is released slowly from tissue stores rather than being rapidly excreted like cyanocobalamin.

Hydroxocobalamin also has unique therapeutic properties beyond standard B12 activity. It is a potent nitric oxide scavenger, making it relevant for conditions involving excess nitric oxide (such as some presentations of chronic fatigue, chemical sensitivity and neurological conditions). It is the form used in medical B12 injections throughout Europe precisely because of its superior retention and dual conversion capability. For those unsure which active B12 form they need, hydroxocobalamin is a versatile choice that lets the body determine the optimal conversion ratio.

Take 1 drop per day in water with food.

The drop can be taken in water, directly on the tongue or sublingually. Hydroxocobalamin's superior retention means it is an excellent choice for those who want to build B12 stores efficiently. For those with identified B12 deficiency, the dose can be increased to 2 to 3 drops daily during the repletion phase.

This form is particularly well suited for those with nitric oxide related conditions, those who cannot tolerate methylcobalamin (which can cause overstimulation in some people with methylation sensitivities) and as a general purpose B12 for those who want the body to direct the conversion.

1 drop contains: %NRV*
Vitamin B12 98 mcg 3920%

† Nutrient Reference Value (NRV*) not established

Purified Water, Hydroxocobalamin.

  • Suitable for men.

  • Suitable for women.

  • Suitable for people under sixteen years of age.

  • If pregnant or breastfeeding consult your healthcare professional before purchasing and consuming this product.

  • Suitable for vegetarians.

  • Suitable for vegans.

  • No gluten containing ingredients.

  • No nut containing ingredients.

  • No dairy containing ingredients.

If you are taking medication consult your prescribing physician before purchasing and consuming supplements.

Store in a refrigerator once opened.

Keep out of reach of children.

Information displayed does not constitute medical advice.

This product should not be used as a substitute for a varied diet.

Once opened, consume within 3 months.

Vitamin B12 Hydroxocobalamin
Quality manufacturing

Quality promise

Why clinical grade matters

  • GMP certified, pharmaceutical grade manufacturing
  • Made in UK cleanroom facilities, ISO 9001 & ISO 14001 accredited
  • No fillers, binders or additives — only active ingredients
  • Fully traceable from raw material to finished product
  • Non-GM, non-irradiated, 100% green energy manufacturing

Evidence

What the research shows

Our Health Reference Library is an ever-growing collection of peer-reviewed research and health guidance.

Research and routine
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Frequently asked questions

Why take Vitamin B12 Hydroxocobalamin?

Vitamin B12 Hydroxocobalamin supports energy production, nervous system function, and stress resilience.

When should I take B vitamins?

Take in the morning with food to support energy throughout the day.

What are signs of B vitamin deficiency?

Common signs include fatigue, brain fog, mood changes, and numbness.

What does methylated mean?

Methylated B vitamins are pre-activated forms your body can use immediately. Important for those with MTHFR gene variations.

Can B vitamins cause anxiety?

Some people are sensitive to certain B vitamins. Start with a lower dose and take with food if you notice overstimulation.

Why do B vitamins turn urine yellow?

Riboflavin (B2) causes bright yellow urine. This is harmless and shows the vitamins are being processed.

Vitamin B12 Hydroxocobalamin

Vitamin B12 Hydroxocobalamin

$28.00