Vitamin B12 Methylcobalamin Capsules
Support nerve function and methylation with the most active form of B12
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90 capsules
90 day supply
per day
Guaranteed additive free
Highest purity
Therapeutically effective
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Have questions about Vitamin B12 Methylcobalamin Capsules?
"How do I know if I need methylcobalamin vs the other B12 forms?"
"I've heard methylcobalamin can cause anxiety. Is that true?"
"My B12 blood test came back normal but I'm still exhausted. Could I still benefit?"
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Support nerve function and methylation with the most active form of B12
Each capsule provides 1000mcg of vitamin B12 as methylcobalamin, the cytoplasmic active form of B12 that serves as a cofactor for the enzyme methionine synthase. This enzyme converts homocysteine to methionine, a reaction that is central to the methylation cycle. Methylation is one of the body's most important biochemical processes, governing gene expression, neurotransmitter production (serotonin, dopamine, noradrenaline), detoxification, myelin sheath maintenance and histamine clearance.
Methylcobalamin is the most commonly recommended active B12 form because methylation dysfunction is widespread (driven by MTHFR gene variants, nutritional deficiencies and high toxic burden). At 1000mcg per capsule, this provides a therapeutic dose appropriate for addressing B12 deficiency, supporting methylation, managing elevated homocysteine and neurological support. The capsule format provides a higher dose than the liquid versions, making it the preferred choice when a substantial daily B12 dose is required. The vegetarian capsule shell makes this suitable for most dietary requirements.
Key benefits:
- Nerve repair and brain function
- Direct methylation no conversion
- Most active form of B12
| Each capsule contains: | %NRV* | |
|---|---|---|
| Vitamin B12 | 1000 mcg | 40000% |
† Nutrient Reference Value (NRV*) not established
Cellulose, Hydroxypropyl Methylcellulose (capsule), Methylcobalamin.
Directions for use:
Take 1 capsule per day with food.
Taking with a meal supports absorption. For those new to methylcobalamin who have known methylation sensitivities (COMT variants, histamine intolerance), start with the liquid form (86.5mcg per drop) as the lower dose allows gentler introduction. Some individuals experience overstimulation, anxiety or insomnia when starting methylcobalamin at high doses, which typically resolves by starting low and increasing gradually.
For comprehensive B12 coverage, pair with Vitamin B12 Adenosylcobalamin Capsules to support both cytoplasmic methylation and mitochondrial energy production simultaneously.
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Suitable for men.
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Suitable for women.
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Suitable for people under sixteen years of age.
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If pregnant or breastfeeding consult your healthcare professional before purchasing and consuming this product.
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Suitable for vegetarians.
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Suitable for vegans.
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No gluten containing ingredients.
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No nut containing ingredients.
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No dairy containing ingredients.
If you are taking medication consult your prescribing physician before purchasing and consuming supplements.
Store in a cool dry place.
Keep out of reach of children.
Information displayed does not constitute medical advice.
This product should not be used as a substitute for a varied diet.
Once opened, consume within 3 months.
Quality promise
Why clinical grade matters
- ✓ GMP certified, pharmaceutical grade manufacturing
- ✓ Made in UK cleanroom facilities, ISO 9001 & ISO 14001 accredited
- ✓ No fillers, binders or additives — only active ingredients
- ✓ Fully traceable from raw material to finished product
- ✓ Non-GM, non-irradiated, 100% green energy manufacturing
Evidence
What the research shows
Our Health Reference Library is an ever-growing collection of peer-reviewed research and health guidance.
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Frequently asked questions
Why take Vitamin B12 Methylcobalamin Capsules?
Vitamin B12 Methylcobalamin Capsules supports energy production, nervous system function, and stress resilience.
When should I take B vitamins?
Take in the morning with food to support energy throughout the day.
What are signs of B vitamin deficiency?
Common signs include fatigue, brain fog, mood changes, and numbness.
What does methylated mean?
Methylated B vitamins are pre-activated forms your body can use immediately. Important for those with MTHFR gene variations.
Can B vitamins cause anxiety?
Some people are sensitive to certain B vitamins. Start with a lower dose and take with food if you notice overstimulation.
Why do B vitamins turn urine yellow?
Riboflavin (B2) causes bright yellow urine. This is harmless and shows the vitamins are being processed.
